Senior Technical Specialist

Roche Switzerland bridges the gap between pharmaceuticals and diagnostics. Important research and development functions are located here. For our long-term client, F. Hoffmann-La Roche AG in Basel, we are looking for a

Background:

At Roche, the team advances science so that everyone has more time with the people they love. Positioned within the Data Management team, a core function of Product Development Data Sciences (PDD), the Senior Technical Specialist will help Roche lead the industry in speed, quality, and efficiency. By joining Roche, the individual will become part of an innovative environment where cutting-edge tools, automation, and next-generation technologies are developed to streamline clinical trial data collection and delivery, accelerating the release of life-saving medicines to patients worldwide.

As a Senior Technical Specialist with a focus on Agentic AI, the individual will design and deploy autonomous AI agents and multi-agent systems to transform how clinical trial data is processed. The role will bridge the gap between state-of-the-art LLM orchestration and strict pharmaceutical regulatory standards, building systems that automate clinical data cleaning, validation, and analysis. This position offers the opportunity to shape a modern, scalable ecosystem where engineering solutions directly drive GxP-compliant, high-impact clinical decisions.

Tasks & Responsibilities:

• Design and deploy sophisticated agentic workflows using frameworks such as LangGraph, CrewAI, or AutoGen to automate complex clinical data management tasks.
• Build collaboration systems where specialised agents (e.g., Planner, Validator, and Protocol Reviewer) resolve end-to-end data challenges through high-quality, testable code and CI/CD pipelines.
• Apply systematic prompt engineering techniques (including Chain-of-Thought, ReAct, and Reflection) to guarantee high-fidelity outputs in a clinical context.
• Deploy AI agents into our cloud environment (AWS) while building and enhancing scalable applications that capture, move, and prepare scientific data.
• Partner with Data Integrity and Quality teams to ensure all agentic decisions are traceable, reproducible, and fully compliant with regulatory standards.
• Create reliable "Human-in-the-loop" (HITL) workflows and tool-calling agents to solve complex, highly regulated data challenges.

Must Haves:

• 5+ years’ experience and a Bachelor’s or advanced degree in Computer Science, Machine Learning, Engineering, or Biomedical Informatics, alongside 8+ years of experience delivering AI/ML solutions plus 3+ years in full-stack software and data engineering 
• Deep proficiency in Python and hands-on experience with AI orchestration frameworks like LangGraph, CrewAI, AutoGen, or LlamaIndex 
• Solid experience with modern data engineering (SQL/NoSQL, APIs), Vector Databases (e.g., Chroma, Pinecone), and optimizing RAG pipelines 
• Strong experience deploying AI systems on AWS, containerization (Docker, Kubernetes), CI/CD pipelines, Git, and service observability (logging, tracing, metrics) 
• A strong understanding of model reproducibility, interpretability, and validation best practices within highly regulated environments
• Excellent problem-solving capabilities with the ability to explain complex technical concepts clearly to diverse global stakeholders
• Fluency in English

Nice to Have:

• Master’s or PhD in Computer Science, AI, or a related quantitative field
• Experience in a highly regulated industry such as Healthcare, FinTech, or Aerospace
• Understanding / Showcasing practical, end-to-end implementation of security frameworks in complex agentic workflows
• Understanding of clinical trial life cycles and data standards
• Familiarity with monitoring tools for system performance, workflow analytics, and MLOps/DevOps best practices
• Contributions to open-source agentic frameworks or internal AI tooling in the automation or productivity space
• Experience to architect scalable solutions in complex environments with multiple existing system integrations
• Experience with other programming languages (e.g., C#, Java, JavaScript, R, RShiny) is considered an advantage
• Sharing your GitHub account, showcasing relevant work, is considered an advantage

What you will be offered:

• An opportunity to work in one of the world's most important pharmaceutical companies
• Modern campus with plenty of green spaces and meeting areas
• Central location in Basel
• Varied job profile
• Further training opportunities through temptraining
• Working in a dynamic and motivated team

If you are interested please send your application documents addressed to Ms Marianne Buser.

Basel-Stadt Computer Science AI Engineering Informatics ML solutions software data engineering AWS Docker Kubernetes